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Erections of sufficient rigidity and duration for satisfactory sexual intercourse occurred in 13 patients (24.1%) at a median maximal dose of 200 mg. Four patients (7.4%) required 150 mg and comprised 2 patients with psychogenic ED and 2 patients with arteriogenic ED. The remaining 9 patients (16.7%) required 200 mg and comprised 2 patients with psychogenic ED, 3 patients with arteriogenic ED, 2 patients with cavernosal veno-occlusive dysfunction and 2 patients with post radical prostatectomy ED. Nine of the 13 patients (69%) who responded chose to continue therapy with sildenafil. Overall, high dose sildenafil was effective in 4 out of 5 patients (80%) with psychogenic ED and 9 out of 49 patients (18.4%) with organic ED ( Table 2 ). Of the 11 patients with post radical prostatectomy ED, 2 patients had undergone a bilateral nerve sparing radical retro-pubic prostatectomy (NSRRP) and one had undergone a unilateral procedure and the remainder non-nerve sparing procedures. The mean interval between surgery and treatment was 5.2 months. High dose sildenafil was effective in 1 man treated with bilateral NSRRP and in 1 man treated with a unilateral NSRRP.

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Mean responses to questions 3 and 4 of the IIEF erectile function domain, the primary end point, were 1.5 and 1.4 at baseline, 2.2 and 1.9 with sildenafil 100 mg, 2.8 and 2.5 with sildenafil 150 mg and 3.0 and 2.9 with sildenafil 200 mg. The mean score for Q3 and Q4 for sildenafil was statistically superior to baseline, overall, in all etiological groups and at all doses ( P <0.001). The overall mean score for Q3 and Q4 for sildenafil 200 mg was statistically superior to sildenafil 100 mg ( P <0.05) but not to sildenafil 150 mg. The mean score for Q3 and Q4 for sildenafil 200 mg was statistically superior to sildenafil 100 mg ( P <0.05) for all etiological groups except post radical prostatectomy ED ( Figures 1 and 2 ). The global assessment by patients whether treatment improved their erections, the secondary end point, was answered in the affirmative at week 4 by 37% on 100 mg, 46.3% on 150 mg and 68% on 200 mg ( Figure 3 ). The incidence of affirmative responses was statistically superior at sildenafil 200 mg compared to 100 mg ( P <0.05).

Response to IIEF erectile function domain Q3 at baseline, sildenafil 100 mg and sildenafil 200 mg.

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Response to IIEF erectile function domain Q4 at baseline, sildenafil 100 mg and sildenafil 200 mg.

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Mean responses to global assessment question (GAQ) with sildenafil 100 mg, 150 mg and 200 mg.

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Thirty four patients (63%) reported adverse effects with maximal dose sildenafil. Eight of these 34 patients (23.5%) reported 1 adverse effect, 14 patients (41.2%) reported 2, 25 patients (29.4%) reported 3 and 2 patients (5.9%) reported 4 or more side effects. Facial flushing was reported by 32 patients (60%), headaches by 19 patients (35%), nasal congestion by 11 patients (20%), dyspepsia by 14 patients (26%), visual disturbances by 5 patients (5%) and dizziness by 5 patients (9%). Visual disturbances comprised transient light sensitivity (2), blue green visual aura (2) and blurred vision (1). Priapism was not reported. No cardiovascular adverse effects were reported within 24 h of taking sildenafil. One patient suffered an acute sub-endocardial myocardial infarction 5 days after last sildenafil use. A subsequent coronary angiogram demonstrated single vessel coronary artery disease involving the left main coronary artery. Two patients experienced exercise related angina pectoris. Neither experienced angina during sexual activity and the time interval between last sildenafil use and onset of angina pectoris was 4 and 9 days, respectively. Both had ST segment depression during exercise stress testing suggestive of coronary artery disease. None of these 3 patients had a prior history of coronary artery disease but all had significant multiple vascular risk factors.

dice:
22 febrero 2014 a las 9:12

Hola, mi niña lanzó mi galaxys3 al agua y me toca esperar tres dias a que me envin un telefono nuevo pero necesito urgente un numero d telefono d una amiga qno lo se d memoria y no se como lo consigo a traves d gmal..como hago por favor…gracias

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dice:
15 abril 2014 a las 12:46

Muy útil la información. Tengo otra duda, y qué pasa si pierdo el móvil y otra persona decide borra mis contactos? También los perderé de gmail? Partiendo de que todo se sincroniza bilateralmente.

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hola cuando voy a hacer una llamada voy a mis contactos y no ,aparece telefono sino el logo de whatsap que debo hacer… ademas me dice que esta sin servicio es un galaxy s3

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GRACIAS FUE DE MUCHA AYUDA

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Consulta: Si mi usuario google la registre con un correo hotmail? donde veo mis contactos? Gracias por el apoyo!!

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Gracias maestrooo

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buenas me estoy cambiando de iphone 4s a samsung grand 2 y mis contactos yo los tengo en hot mail pero tengo otro correo con otros contactos tambien en hot mail, en mi iphone con solo que yo desmarcara contacots en dicha cuenta el iphone me pregunta si los elimino del terminal y le digo si y desaparecen magicamente del iphone y del whatsapp pero en el samsung cuando hago lo mismo siempre me quedan los contacotos con la reseña de que solo los puedo ocultar porque estan enlsados a otras cuentas. si alguienme puede ayudar a resolver este problema se agradesco mucho

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